The antihypertensive and metabolic effects of amlodipine, a new calcium- channel blocker, in combination with hydrochlorothiazide (HCTZ) were compared with. Physician reviewed amlodipine, hydrochlorothiazide, and olmesartan patient information - includes amlodipine, hydrochlorothiazide, and. Amlodipine and hydrochlorothiazide are two of the most popular medications used to treat high blood pressure, but they are fundamentally. Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Call your doctor at once if you have any other serious side effects, such as: eye pain, vision problems; feeling like you might pass out; swelling in your hands, ankles, or feet; urinating less than usual or not at all; pain or burning when you urinate; joint pain or swelling with fever, swollen glands, click aches, unusual thoughts or behavior, patchy skin color, red spots, or skin rash on your face; headache, trouble concentrating, memory problems, weakness, feeling unsteady, hallucinations, fainting, seizure, shallow breathing; chest pain or heavy feeling, pain spreading to the arm or trazodone dosage for dogs, nausea, sweating, general ill feeling; or electrolyte imbalance--nausea, loss of appetite, uneven heart rate, extreme thirst, increased urination, leg discomfort, jerking muscle movements, muscle weakness or limp feeling, confusion, and feeling tired or restless. Amlodipine is a calcium channel blocker that relaxes widens blood vessels and improves blood flow. Email Address. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. If you are taking a number of different medicines, it may be useful to ask your pharmacist for a Medicines Use Review MUR.