WebMD provides information about interactions between Celebrex Oral and nsaid-aspirinmg-ketorolac-non-injection. To examine the opioid dose sparing effect of ketorolac, we compiled . Celecoxib resulted in decreased morphine use for the first 8 hours after. TORADOL is CONTRAINDICATED for the treatment of peri-operative pain in the setting of Celebrex is a registered trademark of G.D. Searle LLC. Cataflam.
Celebrex and toradol - opinion the
In contrast, in a prospective, randomized, double-blinded, placebo-controlled trial of 30 patients undergoing radical prostatectomy, preoperative oral rofecoxib, 50 mg, did not decrease postoperative pain or morphine consumption . This was done to determine whether pooling data provided evidence that ketorolac use was associated with a decreased incidence of the following opioid-related outcomes: vomiting, nausea, whether an antiemetic was given, and whether urinary retention, oxygen supplementation, or pruritus occurred. Compiling the data for all studies provides more power than would be available from single trials. Preoperative ketorolac administration has no preemptive analgesic effect for minor orthopaedic surgery. However, many clinicians hesitate to combine ketorolac with opioids because of potential adverse effects of ketorolac, especially in patients with risk factors for gastropathy and bleeding.