Before taking amlodipine, hydrochlorothiazide, and valsartan, tell your doctor if you have kidney or liver disease, congestive heart failure, glaucoma, asthma or. Rev Med Liege. Jul-Aug;65() [Medication of the month. Exforge HCT: combination of amlodipine besylate, valsartan and hydrochlorothiazide in a . Amlodipine, valsartan, and hydrochlorothiazide is a combination of medicines that is used to treat high blood pressure (hypertension). High blood pressure adds. Valsartan — Hydrochlorothiazide Lithium : Increases in serum lithium concentrations and lithium toxicity have been reported during concomitant administration of lithium with angiotensin II receptor antagonists or thiazides. Gender: Pharmacokinetics of valsartan does not differ significantly between males and females. Do not take in larger or smaller amounts or besylaate longer than recommended. All rights reserved. Hydrochlorothiazide is chemically described as 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazinesulfonamide 1,1-dioxide. Amlodipine is a calcium channel blocker CCB. Investigations: blood uric acid increased, blood creatine phosphokinase increased, weight besy,ate. This information does not replace the advice of a doctor. Fluconazole: May increase the serum concentration of Calcium Channel Blockers. Your doctor may occasionally change your dose. Take trazodone effectiveness medicine as soon as you can, but skip the missed dose if it is almost time for your next dose.